Thesis/Theses examined by Frieß, Wolfgang

Chen, Siyu (2024): Tumor-targeted delivery of Cas9 mRNA and sgRNA against KRAS-mutated lung cancer. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Zhang, Fengrong (2024): Enhancing endosomal escape of siRNA through chemical electron transfer. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Härdter, Nicole (2024): The use of novel polymeric vials for lyophilization of biopharmaceuticals and microwave-assisted freeze-drying. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Groel, Sebastian (2023): Lyophilization process design for protein drugs using α-relaxations and thermal history. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Berner, Carolin (2023): Application of molecular dynamics simulations for developability assessment and formulation development of biologics. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Peng, Lun (2022): Sequence-defined carriers for drug and nucleic acid delivery. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Eisele, Simon (2022): Development of a sprayable hydrogel containing the recombinant bacteriophage endolysin HY-133 for topical MRSA sanitation. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Stelzl, Andreas (2021): Subcutaneous delivery of high concentrated mAb-formulations using novel application systems. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Krieg, Dennis (2021): Development, characterization and stability of therapeutic protein co-formulations. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Gitter, Julian Hendryk (2020): New approaches to optimize freeze-drying of monoclonal antibodies. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Keil, Tobias (2020): Formulation and characterization of siRNA containing polyplexes as dry powder for pulmonary delivery. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Liu, Weiwei (2020): New studies on protein loaded VPG as controlled release systems. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Kuhn, Jasmin (2020): Aminoethylene-lipopeptides for intracellular delivery of gene modulating tools. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Svilenov, Hristo Lyubomirov (2019): Formulation of therapeutic proteins: Protein unfolding, refolding, aggregation and long-term storage stability. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Breitsamer, Michaela (2019): Lipid-based depots: manufacturing, administration and interactions of protein drugs with lipid formulations. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Scherer, Nicole Marion Doris (2019): Leachable and extractable studies on single-use system technologies in commercial scale drug filling lines. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Wanner, Randy (2019): MicroScale Thermophoresis (MST) for protein formulation development. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Reinhard, Sören (2019): Precise biodegradable carriers for nucleic acid delivery. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Vollrath, Ilona (2018): Controlled nucleation and heat flux measurements as innovative technologies for freeze-drying. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Rodrigues Neibecker, Leticia (2018): Development of novel vaccine carriers: physicochemical and biological characterization of hexosomes. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Reinauer, Eva (2018): Design of an anti-inflammatory coating for invasive medical devices. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Morys, Stephan (2018): Optimization of shielding and targeting domains within sequence-defined, cationic carriers for pDNA delivery. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Werner, Benjamin Patrick (2017): Filtration and novel polymeric containers for the improved quality of biotech drug products. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Zhang, Peng (2017): Protein transduction by lipo-oligoaminoamide nanoformulations. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Nawrath, Timon Gregor (2017): Gedächtnisleistungen in Assoziation mit Polymorphismen des FOXP2- Gens. Dissertation, LMU München: Faculty of Medicine

Liu, Xiaowen (2016): Intracellular Protein delivery by defined polycations or combining a targeting ligand with an endosomolytic peptide. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Etzl, Enikö Elsa (2016): Collapse dried protein powders for needle-free ballistic injection. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

He, Dongsheng (2016): Combinatorial optimization of nucleic acid carriers for folate-targeted delivery. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Neuhofer, Christian (2015): Development of lipid based depot formulations using interferon-beta-1b as a model protein. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Anamur, Cihad (2015): Novel formulation approaches for ballistic intradermal vaccination. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Liebner, Robert (2015): Formulation of PEGylated and HESylated biopharmaceuticals. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Mathäs, Roman Willi (2015): Non-spherical micro- and nanoparticles: fabrication, characterization, and in-vitro investigations. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Even, Marie-Paule (2015): Twin-screw extruded lipid implants for vaccine delivery. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Tilgner, Konstantin (2015): Assoziationsuntersuchung von Polymorphismen des DRD1-Gens mit Schizophrenie und präfrontaler exekutiver Funktion. Dissertation, LMU München: Faculty of Medicine

Lächelt, Ulrich (2014): Proton-sponge activity and receptor-targeting of sequence-defined nucleic acid carriers. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Schoch, Angela (2014): Influence of the antibody variable domain on FcRn-dependent pharmacokinetics. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Bosch, Thomas (2014): Aggressive Freeze-Drying: a fast and suitable method to stabilize biopharmaceuticals. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Hildebrandt, Christian (2014): Crystalline Monoclonal Antibodies: Development of stable crystals for drying and sustained release formulations. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Hertel, Sebastian (2014): Pulmonary delivery of pharmaceutical proteins by means of vibrating mesh nebulization. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Sprengholz, Martina (2014): Industrial ram extrusion as innovative tool for the development of biodegradable sustained release implants. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Scholz, Claudia Veronica (2014): Influence of Size and Topology on the Efficiency of Sequence-defined Polycationic Carriers for Gene Delivery. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Geidobler, Raimund (2014): Cyclodextrins as excipients in drying of proteins and controlled ice nucleation in freeze-drying. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Hofer, Markus (2013): Development of spider silk protein particles for pharmaceutical applications. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Härtl, Elisabeth (2013): Novel approaches for stabilization and characterization of therapeutic proteins in liquid formulations. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Deng, Yibin (2013): Investigations on the administration of dry vaccines for epidermal powder injection. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Spalthoff, Veronika Maria (2013): New analytical methods for the assessment of the physical stability of therapeutical proteins. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Troiber, Christina (2013): Sequence-defined polycationic oligomers for nucleic acid delivery. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Freitag, Angelika Juliane (2012): The immunogenicity of protein aggregates: studies on a murine monoclonal antibody in wild-type mice. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Sax, Gerhard Ludwig (2012): Twin-screw extruded lipid implants for controlled drug delivery. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Dohmen, Christian (2012): Precise and multifunctional conjugates for targeted siRNA delivery. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Freitag, Klaus (2010): Preparation of nanodispersions by antisolvent precipitation: a new formulation approach. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Serno, Tim (2010): Inhibition of therapeutic protein aggregation by cyclodextrins. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Youssef Mohamed, Ahmed Moustafa Kamal (2010): Systematic Studies to Correlate Microcalorimetry with Stability Studies on Liquid Formulations of Various Protein Drugs.. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Rosenberg, Eva (2010): Aggregation of therapeutic antibodies in the course of downstream processing. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Philipp, Alexander (2010): Delivery of siRNA with bioresponsive cationic-polymer based carriers. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Schersch, Kathrin Brigitte (2009): Effect of collapse on pharmaceutical protein lyophilizates. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Schwab, Martin (2009): Degradation of lipid based drug delivery systems and characterization of semi-synthetic spider silk proteins for the application in pharmaceutical technology. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Meyer, Martin (2009): Dynamic endosomolytic polymer conjugates for pDNA and siRNA delivery. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Ruß, Verena (2008): Novel degradable pseudodendritic oligoamines for in vitro and in vivo gene delivery. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Lang, Rainer (2008): Virus-Like particle based vaccines: stabilization by freeze-drying and development of sustained relaese devices. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Fella, Carolin (2008): Dynamic and effective gene vectors via pH-sensitive PEG-shielding. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Wiggenhorn, Michael (2007): Scale-Up of Liposome Manufacturing: Combining High Pressure Liposome Extrusion with Drying Technologies. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Zillies, Jan (2007): Gelatin Nanoparticles for Targeted Oligonucleotide Delivery to Kupffer Cells - Analytics, Formulation Development, Practical Application. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Zwiorek, Klaus (2006): Gelatin Nanoparticles as Delivery System for Nucleotide-Based Drugs. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Schimanski, Katrin (2006): Untersuchungen zum Stabilitätsverhalten der therapeutischen Antikörper-Zytokin-Konstrukte huKS-IL 2 und hu14.18-IL 2. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Boeckle, Sabine (2005): Improved nonviral gene vectors: Efficient and non-toxic polyplexes with enhanced endosomolytic activity. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Schmidt, Roland (2005): Topical delivery of alpha1-Antichymotrypsin for wound healing. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Mohl, Silke (2004): The Development of a Sustained and Controlled Release Device for Pharmaceutical Proteins based on Lipid Implants. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Gruber, Friedrich (2004): Untersuchungen zur Enkapsulierung von Paclitaxel in kationische Liposomen. Dissertation, LMU München: Faculty of Chemistry and Pharmacy

Fraunhofer, Wolfgang (2003): Asymmetrical flow field-flow-fractionation in pharmaceutical analytics: investigations in aggregation tendencies of pharmaceutical antibodies. Dissertation, LMU München: Faculty of Chemistry and Pharmacy