| Barthell, Elisabeth (2008): Immunhistochemische Visualisierung von Cathepsin D und Glycodelin A am Mammakarzinom. Dissertation, LMU München: Faculty of Medicine |
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Barthell_Elisabeth.pdf 5MB |
DOI: 10.5282/edoc.9316
Abstract
121 breast cancer tumours were stained immunohistochemically with Cath D mouse antibody and Gd A monoclonal mouse and polyklonal rabbit antibody. For Cath D tumours with positive lymph nodes showed significant higher expression as well as ductal carcinomas compared to lobal carcinomas. For Gd A the monoclonal antibody showed a positive correlation of staining with positive steroid receptors (Estrogen and Progesteron). There was no association with grading. The results fit into the concept of breakdown of extracellular matrix by Cath D and its role in tumour progression and metastasis as well as immunosuression an d the rolr in tumourogenesis of Gd.
| Item Type: | Theses (Dissertation, LMU Munich) |
|---|---|
| Keywords: | Cathepsin D, Glycodelin A, Immunhistochemistry, breast cancer, hormone receptors, |
| Subjects: | 600 Technology, Medicine 600 Technology, Medicine > 610 Medical sciences and medicine |
| Faculties: | Faculty of Medicine |
| Language: | German |
| Date of oral examination: | 20. November 2008 |
| 1. Referee: | Jeschke, Udo |
| MD5 Checksum of the PDF-file: | 34b08454ff6858667eec9036714a7a7f |
| Signature of the printed copy: | 0700/UMD 12929 |
| ID Code: | 9316 |
| Deposited On: | 02. Dec 2008 08:13 |
| Last Modified: | 24. Oct 2020 06:48 |
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