Histone lysine methylation in the context of nuclear architecture

Zinner, Roman (2007): Histone lysine methylation in the context of nuclear architecture. Dissertation, LMU München: Fakultät für Biologie

Abstract

The impact of histone lysine methylation as an essential epigenetic mechanismn for gene regulation has been demonstrated by numerous studies where it was functionally and structurally linked to euchromatin and heterochromatin.In this work the 3D architecture and spatial interrealtionships of different histone lysine methylation sites was investigated in various human cell types.

• Dokumententyp: Dissertationen (Dissertation, LMU München)
• Keywords: lysine methylation, confocal microscopy
• Themengebiete: 500 Naturwissenschaften und Mathematik ; 500 Naturwissenschaften und Mathematik > 570 Biowissenschaften, Biologie
• Fakultäten: Fakultät für Biologie
• Sprache der Hochschulschrift: Englisch
• Datum der mündlichen Prüfung: 25. Juni 2007
• 1. Bericht­erstatter:in: Cremer, Thomas