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Symptomatik und Mediatorfreisetzung nach nasaler Allergenprovokation
Symptomatik und Mediatorfreisetzung nach nasaler Allergenprovokation
This examination is an approach of the allergic late phase reaction via quality of life, acoustic rhinometry, and determination of ECP, IL-5, IL-8, MCP-1, MCP-3, RANTES, sVCAM-1, and LTC4 in nasal secretions. It describes and discusses changes in subjective and objective parameters over a time period of eight hours following nasal allergen application. Data obtained from a clinical and an experimental part is analyzed and statistically compared in reference to the existence of an early and late phase allergic reaction. Results are discussed under consideration of a possible neurological participation in the occurrence and persistence of the allergic inflammatory process.
Allergic late phase reaction, allergic rhinitis, acoustic rhinometry, quality of life, nasal cycle, nasal provocation
Jordan, Thorsten
2004
Deutsch
Universitätsbibliothek der Ludwig-Maximilians-Universität München
Jordan, Thorsten (2004): Symptomatik und Mediatorfreisetzung nach nasaler Allergenprovokation. Dissertation, LMU München: Medizinische Fakultät
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Abstract

This examination is an approach of the allergic late phase reaction via quality of life, acoustic rhinometry, and determination of ECP, IL-5, IL-8, MCP-1, MCP-3, RANTES, sVCAM-1, and LTC4 in nasal secretions. It describes and discusses changes in subjective and objective parameters over a time period of eight hours following nasal allergen application. Data obtained from a clinical and an experimental part is analyzed and statistically compared in reference to the existence of an early and late phase allergic reaction. Results are discussed under consideration of a possible neurological participation in the occurrence and persistence of the allergic inflammatory process.