Symptomatik und Mediatorfreisetzung nach nasaler Allergenprovokation

Jordan, Thorsten (2004): Symptomatik und Mediatorfreisetzung nach nasaler Allergenprovokation. Dissertation, LMU München: Faculty of Medicine

Abstract

This examination is an approach of the allergic late phase reaction via quality of life, acoustic rhinometry, and determination of ECP, IL-5, IL-8, MCP-1, MCP-3, RANTES, sVCAM-1, and LTC4 in nasal secretions. It describes and discusses changes in subjective and objective parameters over a time period of eight hours following nasal allergen application. Data obtained from a clinical and an experimental part is analyzed and statistically compared in reference to the existence of an early and late phase allergic reaction. Results are discussed under consideration of a possible neurological participation in the occurrence and persistence of the allergic inflammatory process.

• Item Type: Theses (Dissertation, LMU Munich)
• Keywords: Allergic late phase reaction, allergic rhinitis, acoustic rhinometry, quality of life, nasal cycle, nasal provocation
• Subjects: 600 Technology, Medicine; 600 Technology, Medicine > 610 Medical sciences and medicine
• Faculties: Faculty of Medicine
• Language: German
• Date of oral examination: 21. October 2004
• 1. Referee: Rasp, Gerhard
• Signature of the printed copy: 0700/UMD 10729