Symptomatik und Mediatorfreisetzung nach nasaler Allergenprovokation

Jordan, Thorsten (2004): Symptomatik und Mediatorfreisetzung nach nasaler Allergenprovokation. Dissertation, LMU München: Medizinische Fakultät

Abstract

This examination is an approach of the allergic late phase reaction via quality of life, acoustic rhinometry, and determination of ECP, IL-5, IL-8, MCP-1, MCP-3, RANTES, sVCAM-1, and LTC4 in nasal secretions. It describes and discusses changes in subjective and objective parameters over a time period of eight hours following nasal allergen application. Data obtained from a clinical and an experimental part is analyzed and statistically compared in reference to the existence of an early and late phase allergic reaction. Results are discussed under consideration of a possible neurological participation in the occurrence and persistence of the allergic inflammatory process.

• Dokumententyp: Dissertationen (Dissertation, LMU München)
• Keywords: Allergic late phase reaction, allergic rhinitis, acoustic rhinometry, quality of life, nasal cycle, nasal provocation
• Themengebiete: 600 Technik, Medizin, angewandte Wissenschaften ; 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit
• Fakultäten: Medizinische Fakultät
• Sprache der Hochschulschrift: Deutsch
• Datum der mündlichen Prüfung: 21. Oktober 2004
• 1. Bericht­erstatter:in: Rasp, Gerhard