| Wagner, Sandra (2020): Glykosylierungen des Thyroxin-bindenden Globulins. Dissertation, LMU München: Faculty of Medicine |
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Wagner_Sandra.pdf 3MB |
DOI: 10.5282/edoc.27116
Abstract
Removal of N-glycosylation consensus sequences in hTBG-gene (SERPINA7-gene) results in no alteration in protein folding and binding of T4 . Destroying of all five N-glycosylation sites at once in the amino acid chain inhibits completely the export into the extracellular space but contrary any kind of glycosylation is actually basic and obviously needed for export from the cell. Non-glycosylated TBG is not exported into the medium.
| Item Type: | Theses (Dissertation, LMU Munich) |
|---|---|
| Keywords: | TBG, Thyroxin, thyroxine, N-Glykosylierung, N-glycosylation, Proteinreifung, Proteinfaltung, protein folding, export of proteins |
| Subjects: | 600 Technology, Medicine 600 Technology, Medicine > 610 Medical sciences and medicine |
| Faculties: | Faculty of Medicine |
| Language: | German |
| Date of oral examination: | 13. November 2020 |
| 1. Referee: | Gärtner, Roland |
| MD5 Checksum of the PDF-file: | 4ea9bccf7a3dc85354c96d6585d0c0d8 |
| Signature of the printed copy: | 0700/UMD 19441 |
| ID Code: | 27116 |
| Deposited On: | 26. Jan 2021 15:26 |
| Last Modified: | 26. Jan 2021 15:26 |
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