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Effects of a carbohydrate restricted diet on the metabolic state and progressive pancreatic beta-cell loss in transgenic mice expressing a dominant negative GIP receptor
Effects of a carbohydrate restricted diet on the metabolic state and progressive pancreatic beta-cell loss in transgenic mice expressing a dominant negative GIP receptor
Aim of this study was to investigate the effects of a carbohydrate restricted diet on the metabolic state and the progressive loss of beta-cells in transgenic mice expressing a dominant negative GIP receptor. The expression pattern of the endogene and trasngenic GIP receptor, clinical parameters, and the number of beta-cells and islets were investigated among other things.
GIP, diabetes, beta-cell number, islet number
Höfer, Martina
2007
English
Universitätsbibliothek der Ludwig-Maximilians-Universität München
Höfer, Martina (2007): Effects of a carbohydrate restricted diet on the metabolic state and progressive pancreatic beta-cell loss in transgenic mice expressing a dominant negative GIP receptor. Dissertation, LMU München: Faculty of Veterinary Medicine
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Abstract

Aim of this study was to investigate the effects of a carbohydrate restricted diet on the metabolic state and the progressive loss of beta-cells in transgenic mice expressing a dominant negative GIP receptor. The expression pattern of the endogene and trasngenic GIP receptor, clinical parameters, and the number of beta-cells and islets were investigated among other things.