| Ganiek, Maximilian (2018): Metalation and Halogen-Lithium exchange of sensitive substrates and mild ester homologation in continuous flow. Dissertation, LMU München: Faculty of Chemistry and Pharmacy |
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Ganiek_Maximilian.pdf 8MB |
DOI: 10.5282/edoc.23179
Abstract
Microflow setups offer enhanced residence time control, mixing, and heat transfer compared to batch chemistry. These features make them ideal for reactions employing unstable, highly reactive reagents. This work focused on applying these features of continuous flow setups to metalation, halogen-metal exchange and enolate chemistry. Additionally, the synthesis and derivatization of a novel heterocyclic scaffold by batch methods was described.
| Item Type: | Theses (Dissertation, LMU Munich) |
|---|---|
| Keywords: | Metalorganic reagents, Organic synthesis, Continuous flow microreactors |
| Subjects: | 500 Natural sciences and mathematics 500 Natural sciences and mathematics > 540 Chemistry and allied sciences |
| Faculties: | Faculty of Chemistry and Pharmacy |
| Language: | English |
| Date of oral examination: | 18. October 2018 |
| 1. Referee: | Knochel, Paul |
| MD5 Checksum of the PDF-file: | 7fb91907c8c7752b02674d86686b1cb1 |
| Signature of the printed copy: | 0001/UMC 25939 |
| ID Code: | 23179 |
| Deposited On: | 27. Nov 2018 08:20 |
| Last Modified: | 23. Oct 2020 16:31 |
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