| Barthell, Elisabeth (2008): Immunhistochemische Visualisierung von Cathepsin D und Glycodelin A am Mammakarzinom. Dissertation, LMU München: Faculty of Medicine |
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Barthell_Elisabeth.pdf 5Mb |
Abstract
121 breast cancer tumours were stained immunohistochemically with Cath D mouse antibody and Gd A monoclonal mouse and polyklonal rabbit antibody. For Cath D tumours with positive lymph nodes showed significant higher expression as well as ductal carcinomas compared to lobal carcinomas. For Gd A the monoclonal antibody showed a positive correlation of staining with positive steroid receptors (Estrogen and Progesteron). There was no association with grading. The results fit into the concept of breakdown of extracellular matrix by Cath D and its role in tumour progression and metastasis as well as immunosuression an d the rolr in tumourogenesis of Gd.
| Item Type: | Thesis (Dissertation, LMU Munich) | |
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| Keywords: | Cathepsin D, Glycodelin A, Immunhistochemistry, breast cancer, hormone receptors, | |
| Subjects: | 600 Technology, Medicine 600 Technology, Medicine > 610 Medical sciences and medicine | |
| Faculties: | Faculty of Medicine | |
| Language: | German | |
| Date Accepted: | 20. November 2008 | |
| 1. Referee: | Jeschke, Udo | |
| Persistent Identifier (URN): | urn:nbn:de:bvb:19-93161 | |
| MD5 Checksum of the PDF-file: | 34b08454ff6858667eec9036714a7a7f | |
| Signature of the printed copy: | 0700/UMD 12929 | |
| ID Code: | 9316 | |
| Deposited On: | 02. Dec 2008 08:13 | (UTC) |
| Last Modified: | 16. Oct 2012 08:22 | (UTC) |
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